Nearly all of the land area in this watershed is within incorporated municipalities. Forty-two percent of the land is covered by urban uses. Grasslands (22%), agriculture (17%) forests (8%) and wetlands (7%) make up most of the remaining land uses.

Stream and wetland modification, urban and rural runoff, construction site erosion and industrial point sources of pollution are the major contributors to degraded water and habitat quality within this watershed. Over eight miles of stream are listed on the 303(d) list as impaired. Many streams in this watershed have been concrete-lined, or straightened to convey floodwaters off the land faster. Flooding continues to be a major concern in this watershed. The Milwaukee Metropolitan Sewerage District is implementing several flood control projects in this watershed. Over five miles of the Little Menomonee River has been designated as the Moss American Superfund Site. Creosote contaminated sediments within the river have caused extensive environmental damage, and negotiations are underway with U.S. EPA and the responsible party for implementing a clean up remedy.